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Post-doc in the AMIB team at LIX (École
Polytechnique), France.
Contact
Research keywords
systems biology,
abstract interpretation,
static analysis,
stochastic processes,
parameters inference,
biological regulatory networks.
Projects
- The Process Hitting Framework
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Joint work with
Morgan Magnin and Oliver Roux
(IRCCyN, Nantes, France).
Framework for concurrent processes modelling, allowing scalable formal dynamics checking (static analysis and abstract interpretation techniques).
Application to very large biological regulatory networks.
Software Pint available at processhitting.wordpress.com.
Related publications: [PMR12-MSCS] [PMR10-TCSB] [PMR10-SASB].
- Stochastic simulation of process calculi
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Joint work with
Matthew R. Lakin and
Andrew Phillips (Microsoft Research, Cambridge, UK).
Software SPiM available at research.microsoft.com/projects/spim.
Related publications: [LPP12-TCS] [PYLP10-CMSB] [PLP10-MeCBIC].
Talks
- ETH Zurich/BISON seminar,
Abstract Modelling and Analysis of Large Biological Regulatory Networks.
April 2012, Zurich, Switzerland.
[ slides ].
- LIP6/MoVe seminar,
Efficient Static Analysis of Dynamical Properties using the Process Hitting.
January 2012, Paris, France.
[ slides ].
- Hôpital
Raymond Poincaré - Service d'oncologie pédiatrique (staff),
Introduction à la science informatique pour l'étude des systèmes dynamiques.
November 2011, Garches, France.
[ slides ].
- AFSEC seminar,
Modelling, Simulation and Verification of Large Biological Regulatory Networks.
October 2011, Paris, France.
[ slides ].
- Soutenance de thèse de doctorat, Modélisation, Simulation et Vérification des Grands Réseaux de Régulation Biologique, Octobre 2011, Nantes, France
[ slides ].
- SASB 2011,
Static Analysis of Boolean Networks Based on Interaction Graphs: a Survey.
September 2011, Venice, Italy.
[ slides ].
- University of Luxembourg (SaToSS Team),
Modelling, Simulation and Model Checking of Large Biological Regulatory Networks.
July 2011, Luxembourg.
- LIX (AMIB Team),
Modelling, Simulation and Model Checking of Large-Scale Biological Regulatory Networks.
June 2011, Paris, France.
[ slides ].
- DTU/MT-LAB (LBT Team),
Modelling, Simulation and Large-Scale Model Checking of Biological Regulatory Networks.
March 2011, Lyngby, Copenhaguen, Denmark.
[ slides ].
- LIENS/Working Group Computational Biology,
Abstract interpretation of Biological Regulatory Networks dynamics.
January 2011, Paris, France.
[ slides ].
- LIF/MoVe Working Group,
Modelling and checking large scale biological regulatory networks.
November 2010, Marseille, France.
[ slides ].
- CMSB 2010,
A Generic Abstract Machine for Stochastic Process Calculi.
September 2010, Trento, Italy.
[ slides ].
- SASB 2010,
Abstract interpretation of dynamics of biological regulatory networks.
September 2010, Perpignan, France.
[ slides ].
- JOBIM 2010 satellite meeting : Dynamical modelling and simulation of biological networks,
Abstract interpretation of dynamics of biological regulatory networks.
September 2010, Montpellier, France.
[ slides ].
- Journée des doctorants de l'ED STIM,
Modélisation et Vérification des Réseaux de Régulations entre Gènes.
April 2010, Nantes, France.
Best presentation award.
[ slides ].
- Biogenouest integrative genomics project,
Modélisation, Simulation, Vérification et Contrôle des Grands
Réseaux de Régulation Génique.
April 2010, Nantes, France.
[ slides ].
- Workshop "Modélisation dynamique et simulation des réseaux biologiques",
Refining Dynamics of Gene Regulatory Networks in a Stochastic π-Calculus Framework.
June 2009, Nantes, France.
[ slides ].
- Workshop "Constructing gene networks", Stochastic π-calculus modelling of gene regulatory networks. January 2009, Paris, France. [ slides ].
- Workshop MaReBio'08, Temporal parameters within π-calculus modelling of gene regulatory networks. November 2008, Marseille, France. [ slides ]
- Soutenance de master recherche, Réseaux géométriques pour l'indexation et la recherche en grandes dimensions. June 2008, Rennes, France. [ slides ]
Publications
International Journals
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[PMR12-MSCS]
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Loïc. Paulevé, Morgan Magnin, and Olivier Roux.
Static analysis of biological regulatory networks dynamics using
abstract interpretation.
Mathematical Structures in Computer Science, in press, 2012.
Preprint available at http://loicpauleve.name/mscs.pdf.
[ bib |
DOI |
.pdf ]
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[LPP12-TCS]
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Matthew R. Lakin, Loïc Paulevé, and Andrew Phillips.
Stochastic simulation of multiple process calculi for biology.
Theoretical Computer Science, 431:181 - 206, 2012.
[ bib |
DOI |
.pdf ]
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[PMR10-TSE]
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Loïc Paulevé, Morgan Magnin, and Olivier Roux.
Tuning Temporal Features within the Stochastic
π-Calculus.
IEEE Transactions on Software Engineering, 37(6):858-871,
2011.
[ bib |
DOI |
.pdf ]
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[PR10-CRAS]
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Loïc Paulevé and Adrien Richard.
Topological Fixed Points in Boolean Networks.
Comptes Rendus de l'Académie des Sciences - Series I -
Mathematics, 348(15-16):825 - 828, 2010.
[ bib |
DOI |
.pdf ]
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[PMR10-TCSB]
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Loïc Paulevé, Morgan Magnin, and Olivier Roux.
Refining dynamics of gene regulatory networks in a stochastic
π-calculus framework.
In Corrado Priami, Ralph-Johan Back, Ion Petre, and Erik de Vink,
editors, Transactions on Computational Systems Biology XIII, volume
6575 of Lecture Notes in Computer Science, pages 171-191. Springer
Berlin / Heidelberg, 2011.
[ bib |
DOI |
.pdf ]
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[PJA10]
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Loïc Paulevé, Hervé Jégou, and Laurent Amsaleg.
Locality sensitive hashing: A comparison of hash function types and
querying mechanisms.
Pattern Recognition Letters, 31(11):1348 - 1358, 2010.
[ bib |
DOI |
.pdf ]
International Conferences and Workshops
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[PR11-SASB]
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Loïc Paulevé and Adrien Richard.
Static analysis of boolean networks based on interaction graphs: a
survey.
Electronic Notes in Theoretical Computer Science, In press,
2011.
Proceedings of The Second International Workshop on Static
Analysis and Systems Biology (SASB 2011).
[ bib |
.pdf ]
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[PMR10-SASB]
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Loïc Paulevé, Morgan Magnin, and Olivier Roux.
Abstract Interpretation of Dynamics of Biological
Regulatory Networks.
Electronic Notes in Theoretical Computer Science, 272:43-56,
2011.
Proceedings of The First International Workshop on Static
Analysis and Systems Biology (SASB 2010).
[ bib |
DOI |
.pdf ]
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[PYLP10-CMSB]
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Loïc Paulevé, Simon Youssef, Matthew R. Lakin, and Andrew Phillips.
A generic abstract machine for stochastic process calculi.
In CMSB '10: Proceedings of the 8th International Conference on
Computational Methods in Systems Biology, pages 43-54, New York, NY, USA,
2010. ACM.
[ bib |
DOI |
.pdf ]
Invited Papers
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[PLP10-MeCBIC]
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Andrew Phillips, Matthew Lakin, and Loïc Paulevé.
Stochastic simulation of process calculi for biology.
In Gabriel Ciobanu and Maciej Koutny, editors, Proceedings
Fourth Workshop on Membrane Computing and Biologically Inspired Process
Calculi 2010, volume 40 of EPTCS, pages 1 - 5, 2010.
invited paper.
[ bib |
DOI |
.pdf ]
Reports
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[PaulevePhD]
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Loïc Paulevé.
Modélisation, Simulation et Vérification des Grands
Réseaux de Régulation Biologique.
PhD thesis, École Centrale de Nantes, 2011.
[ bib |
http ]
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[PMR11-RR-SAAI]
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Loïc Paulevé, Morgan Magnin, and Olivier Roux.
Static Analysis by Abstract Interpretation of Biological
Regulatory Networks Dynamics.
Research Report hal-00574353, IRCCyN, March 2011.
[ bib |
http ]
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[PMR09-RR-Tuning]
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Loïc Paulevé, Morgan Magnin, and Olivier Roux.
Tuning Temporal Features within the Stochastic
π-Calculus.
Research Report hal-00397308, IRCCyN, June 2009.
[ bib |
http ]
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[PMR09-RR-Refining]
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Loïc Paulevé, Morgan Magnin, and Olivier Roux.
Refining Dynamics of Gene Regulatory Networks in a
Stochastic π-Calculus Framework.
Research Report hal-00397235, IRCCyN, June 2009.
[ bib |
http ]
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[PauMasterThesis]
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Loïc Paulevé.
Euclidean lattices for high dimensional indexing and searching.
Research report, IRISA, 2008.
[ bib |
http ]
Co-authors
(by date/name)
Awards
Teaching
Other activities
Education
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